Tangerine Red Pill and Er Chen Pill are both effective in expectorating phlegm, and these two medicines are completely different in terms of composition and efficacy, and are not comparable. Although both Tangerine Red Pill and Er Chen Pill can expectorate phlegm, Tangerine Red Pill has the efficacy of clearing the lungs and moistening the dryness, stopping coughing and resolving phlegm, and is suitable for phlegm and shortness of breath caused by lung-heat and dry cough. Tangerine Red Pill is composed of 15 Chinese medicines, such as Hua Tangerine Red, Semixia, Chen Pi, etc. This medicine is also effective in treating bitter mouth and dry phlegm caused by lung heat, and should not be used by those who have coughs caused by qi deficiency and dry cough caused by yin deficiency. Er Chen Pill is composed of Chen Pi, Pinellia, Poria and Glycyrrhiza glabra, which is also effective in treating chest and epigastric distension, nausea and vomiting caused by phlegm-dampness stagnation, and should not be used by people with dry cough caused by lung yin deficiency. Er Chen Pill has the effect of drying dampness and resolving phlegm (removing phlegm from the body by drying dampness), regulating qi and harmonizing the stomach, and is suitable for coughing and phlegm caused by phlegm-dampness stagnation. These two medicines don’t have the same direction of phlegm expectoration, and although their respective expectorant effects are good, there is no comparability between the two medicines. Tangerine Red Pill and Er Chen Pill should not be used together with tonic Chinese medicines, and the side effects are not yet clear. These two medicines are non-prescription medicines, and their use must be in accordance with the doctor’s advice or the instructions of the medicines.