Abstract: The clinical presentation, combined with echocardiography and ventriculography, often confirms the diagnosis of hypertrophic cardiomyopathy. The examination of hypertrophic cardiomyopathy reveals an enlargement of the turbinate to the left, a shift of the apical beats to the lower left, and an elevated impulse. The early manifestations of hypertrophic cardiomyopathy are dyspnea, weakness and palpitations after exertion. Angina pectoris is also common, and nitroglycerin is not effective. Syncope is a sign of severe disease, and heart failure, often combined with atrial fibrillation, may occur in advanced stages. Hypertrophic cardiomyopathy is characterized by hypertrophy of the ventricular muscle, especially asymmetric hypertrophy of the ventricular septum, which can partially cause obstruction of the ventricular outflow tract. It can be divided into obstructive and non-obstructive hypertrophic cardiomyopathy according to the presence or absence of left ventricular outflow tract obstruction. Asymmetric septal hypertrophy causing subaortic stenosis is called idiopathic hypertrophic subaortic stenosis. Arrhythmias are common complications of hypertrophic cardiomyopathy, with ventricular arrhythmias and atrial fibrillation being the most important and requiring treatment. A small number of patients with hypertrophic cardiomyopathy experience sudden death, which may not be preceded by any signs. Systematic evaluation may help to identify such high-risk patients. Examination of hypertrophic cardiomyopathy: The clinical presentation, combined with echocardiography and ventriculography, often confirms the diagnosis of hypertrophic cardiomyopathy. In hypertrophic cardiomyopathy, the examination reveals an enlargement of the turbinate to the left, a shift of the apical beats to the lower left, and an elevated impulse. The apical double beat may be present. On auscultation of the apical medial aspect of the lower left sternal border, a mid- or late-systolic jet murmur may be heard, propagating toward the apex but not toward the base of the heart, and may be accompanied by systolic tremor. Ancillary tests for hypertrophic cardiomyopathy: ECG: The most common manifestation is left ventricular hypertrophy with ST-T changes, often with huge inverted T waves centered on V and V. Chest X-ray: heart size is normal or enlarged, heart size is proportional to the pressure step difference between the heart and the left ventricular outflow tract, the larger the pressure step difference, the larger the heart is, heart left ventricular hypertrophy is predominant, aorta is not widened, pulmonary artery segment is mostly not significantly prominent, pulmonary stasis is mostly mild, mitral valve calcification is common. Echocardiography is important for the diagnosis of this disease. It can show asymmetric hypertrophy of the ventricular septum, narrowing of the left ventricular cavity, narrowing of the outflow tract and left ventricular diastolic dysfunction to help the diagnosis. Cardiac catheterization: There is a pressure step difference between the left ventricle and the left ventricular outflow tract, and the end-diastolic pressure of the left ventricle is increased. Cardiac angiography; when septal muscle hypertrophy is obvious, the ventricular cavity is seen to have narrow slit-like changes. Aberrant hypertrophy and disorganized arrangement of cardiomyocytes also help to diagnose hypertrophic cardiomyopathy.