Coronary heart disease three branches of the lesions of the treatment methods mainly include drug treatment, surgical treatment and so on. 1. Drug treatment: during the period of illness, we should pay attention to prevent the formation of blood clots, can follow the doctor’s instructions to use aspirin, clopidogrel and other drugs. During the period of illness, patients are prone to myocardial ischemia, can follow the doctor’s instructions to use nitroglycerin, isosorbide nitrate and other drugs, in order to expand the coronary arteries, increase the blood flow of the coronary arteries, improve myocardial ischemia. 2. Surgery: patients with more serious conditions need to rebuild coronary blood flow through surgical treatment. Commonly used clinical treatments include percutaneous coronary intervention and coronary artery bypass grafting. In addition, it is recommended that patients with three branches of coronary artery disease should go to the cardiology department of the hospital as soon as possible and receive treatment under the guidance of professional doctors.