The reference range for reticulocyte hemoglobin content is 28.00 to 36.00 pg. Reticulocyte hemoglobin content is an indicator of iron deficiency and iron-restricted erythropoiesis. The life span of reticulocytes is short, only 1~2 days, so the hemoglobin content of reticulocytes decreases faster when iron deficiency occurs, so the measurement of this index can reflect the change of hemoglobin synthesis more sensitively. After anemic patients are treated with iron preparations such as ferrous succinate, if it is effective, the reticulocyte hemoglobin content will change after 1 day, i.e., this index can reflect the increase of hemoglobin in the early stage, so the reticulocyte hemoglobin content is considered to be a valuable index to determine the early stage of functional iron deficiency, iron-deficient red lineage hematopoiesis, and iron-deficiency anemia. If the patient’s reticulocyte hemoglobin level is abnormal, it is recommended to actively seek medical treatment, complete the relevant examinations, and be diagnosed by the doctor with the combination of the patient’s symptoms and examination results, and the patient should not diagnose on his own in order to avoid delaying the condition.