Chinese medicine believes that “dry mouth in the middle of the night” is mostly related to yin deficiency and internal heat, and can be treated with proprietary Chinese medicines that have the effect of nourishing yin and clearing heat (nourishing yin essence and clearing away heat), such as fluid-enhancing granules and Zhi Bai Di Huang Wan. Since Chinese medicine treatment focuses on evidence-based treatment, there is no such thing as “Chinese patent medicine for dry mouth in the middle of the night”, and it needs to be analyzed in the context of the condition and other factors. 1. Liquid-enhancing granules: this medicine is composed of XuanShen, DiHuang, Maidong, etc. It has the function of nourishing yin and generating fluids, clearing heat and moistening dryness. It can be used to treat symptoms such as dry mouth, dry tongue, dry stools and other symptoms caused by heat and fluid deficiency, as well as the depletion of body fluids caused by high fever in infectious diseases. The adverse effects of the drug are not clear. It can be used in the treatment of yin deficiency and fire exuberance (deficiency of yin essence in the body, resulting in hyperactive fire), hot flashes (a burst of fever), night sweating, dry mouth and sore throat, tinnitus, spermatorrhea, and short and red urination (small amount of urination, dark yellow in color), and other diseases. The drug should be used with caution for pregnant women. At the same time, the drug should not be taken at the same time with cold and flu medicines. Patients with dry mouth are advised to go to regular hospitals for treatment under the guidance of professional physicians.