Parkinson’s eyes can not be opened, it may be a mask face, it may also be caused by eyelid disuse and so on. 1. Mask face: Parkinson’s belongs to neurodegenerative diseases, manifested by resting tremor, limb muscle stiffness, reduced sense of smell, unclear speech, slow reaction, gait or posture disorders, etc. Due to the aggravation of the disease, there may be stiffness of facial muscles, reduced blinking, dull expression, like wearing a mask, and there may be difficulty in opening the eyes. 2. Eyelid disuse: Eyelid disuse (inability to open the eyes) due to lesions in the basal ganglia, a brain structure associated with Parkinson’s disease, usually occurs either voluntarily or involuntarily with eyelid closure. The inability to voluntarily open the eyes, non-paralyzing, without obvious visible contraction of the orbicularis oculi muscles, such as involuntary eye closure that occurs with yawning, is followed by an inability to open the eyelids. Yet, when the eyes are opened, they are not induced when blinking naturally. In Parkinson’s patients, the inability to open the eyes can sometimes be treated by increasing the dose of levodopa; in more severe cases, a pacemaker may need to be implanted, and the parameters can be adjusted in patients who already have a pacemaker implanted. If there is a combination of eye spasms, Botulinum toxin is often used. Parkinson’s disease patients can not open their eyes, it is recommended to go to the neurology department of regular hospitals as soon as possible, with professional doctors to carry out examinations, for the condition of reasonable analysis and judgment, and timely development of the next step in the treatment plan.