Albinism is a genetic disorder in which melanin synthesis is impaired in the body. When albinism occurs, it is important to note that albinism has visual impairment and skin manifestations. Visual impairment includes nystagmus, photophobia, eye discoloration, and poor visual acuity. Most albinos have a wide variation in hair color, which can be white, yellow, brown, red, or even black, and in some cases, the hair color is white for life. Of course, there are some people whose hair color deepens as they age. In addition, albinos tend to develop sun spots such as freckles on the surface of the skin because of the lack of melanin. Albinos are also prone to sunburn when exposed to the sun, but they do not get a tan. Albinism may also involve the heart and other organs and systems, and develop chronic inflammation or fibrosis.