Gram-negative bacilli is a classification of bacteria in which bacilli are derived from a morphological classification that refers to a class of bacteria in which they are rod-shaped. Gram-negative refers to a staining method that can stain bacteria red or pink. So Gram-negative rods are a type of bacteria, more commonly known as E. coli, S. dysenteriae, S. typhi, etc. Some of these bacteria exist in the human body with the outside world, such as the mouth, nasal cavity, gastrointestinal tract and other places, generally do not cause harm to the organism, belong to the normal flora. However, when the body’s defenses are reduced, these flora will be attracted to the surface of the human skin mucous membrane, through direct or blood-borne transmission and other ways to cause disease. Common diseases such as respiratory infections cause pneumonia, Legionnaires’ disease; digestive tract infections cause enteritis, other aspects may also cause urinary tract infections, vaginitis, pelvic inflammatory disease. Therefore, if there is fever, weakness, abdominal pain, diarrhea, blood in the stool and other discomforts, it is important to seek medical attention and actively treat under the guidance of a doctor. Treatment of gram-negative bacilli is mainly based on sensitive antibiotics, that is, through the results of bacterial culture and drug sensitivity test, standardized selection of antibacterial drug treatment, commonly there are third-generation cephalosporins, such as cefixime, ceftriaxone, etc., and quinolone antibiotics, such as levofloxacin, moxifloxacin.