Baby hand, foot and mouth disease is an infectious disease caused by enterovirus infection, its symptoms are generally hands, feet, mouth and other parts of the rash, herpes and accompanied by fever, a small number of children can be combined with aseptic meningitis, encephalitis, respiratory infections, etc., the treatment is usually symptomatic treatment is given priority to. Clinically, children with hand-foot-mouth disease are mostly characterized by the appearance of rash and herpes on the skin of hands and feet, oropharynx, and may be accompanied by fever, and a small number of children with more severe symptoms may be combined with aseptic meningitis, encephalitis, myocarditis, respiratory infections, etc., and may even develop rapidly in a short period of time, which may be life-threatening. Currently, there is no specific antiviral drug or specific treatment, and symptomatic treatment is usually the mainstay. Early-stage children can use ribavirin intravenous drip under the guidance of physicians, which has a certain therapeutic effect. For children who have developed severe meningitis and encephalitis, medications (e.g., mannitol, furosemide, etc.) are required to control the patient’s cranial pressure, and glucocorticosteroids (e.g., methylprednisolone, hydrocortisone, etc.) are used as appropriate. If HFMD is diagnosed, early and standardized treatment is recommended to minimize the adverse effects of the disease.