Saliva with blood spit a few times and then well may be associated with bleeding gums, acute pharyngitis, esophageal mucosal injury and other reasons. 1. Gingival bleeding: when patients suffer from gingivitis or periodontitis and other diseases, the gums will easily bleed when subjected to external stimuli, such as eating or brushing teeth. Patients can develop good hygiene habits, wash the mouth with saline, and follow the doctor’s instructions with 1% hydrogen peroxide solution with chlorhexidine gargle treatment. 2. Acute pharyngolaryngitis: patients with acute pharyngolaryngitis due to bacterial or viral infections may damage the laryngeal mucosa, causing blood in the saliva. Patients can take oral acyclovir or nebulized inhalation dexamethasone, gentamicin and other treatments under the guidance of physicians. 3. Esophageal mucosal injury: due to improper eating, hepatitis and other reasons, damage to the esophageal mucosa, there will also be blood in saliva. Patients can follow the doctor’s instructions with omeprazole, rehabilitation of new liquid and other treatment. If the patient with blood in the saliva spit a few times and well, the symptoms continue to be unrelieved to consult a doctor in a timely manner, to identify the cause of the disease, and related treatment.