Due to the different degrees of disease and illness, methylprednisolone sodium succinate effect time there is a certain difference, usually in the administration of about 4 to 6 hours after the effect can be seen, it is recommended that the actual situation shall prevail, need to be combined with the patient’s specific medical condition by a professional doctor to make a comprehensive judgment. Methylprednisolone sodium succinate belongs to the glucocorticoid class of drugs, with anti-inflammatory, analgesic, antipyretic effect. Clinically, it is mostly used in rheumatoid arthritis and other rheumatic diseases as short-term auxiliary drugs; systemic lupus erythematosus and other immune complex diseases in the critical or maintenance phase of the treatment; pemphigus and other skin diseases and contact dermatitis and other allergic diseases, such as treatment. The time to effect of Methylprednisolone Sodium Succinate varies somewhat depending on the disease and the extent of the condition. The plasma half-life of methylprednisolone sodium succinate is 2.3~4 hours, and the effect is usually seen after about 4~6 hours of administration, which is recommended to be based on the actual situation, and should be combined with the patient’s specific medical condition to be made by a professional doctor to make a comprehensive judgment. This product can cause peptic ulcer bleeding, hypertension, hyperglycemia, osteoporosis and other adverse reactions. It is contraindicated in systemic mycobacterial infections and those with known hypersensitivity to the drug components. Attention to children, diabetes, hypertension, mental illness, certain infectious diseases and other special risk groups of patients should be taken close medical supervision and should be as short as possible course of treatment. It is recommended to use Methylprednisolone Sodium Succinate in accordance with medical advice to avoid adverse consequences.