Ureaplasma urealyticum infection can be treated with moxifloxacin hydrochloride. If there are urogenital symptoms such as frequent urination, urinary urgency, increased urethral discharge, it is recommended that a drug sensitivity test be done first, and sensitive antimicrobial drugs be selected according to the results of the sensitivity for treatment. If there are no uncomfortable symptoms, only for carriers can not need special treatment. Moxifloxacin hydrochloride is the fourth generation of fluoroquinolones, which has broad-spectrum antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, anaerobic bacteria, acid-resistant bacteria, Mycoplasma, Chlamydia, and Legionella, with low inhibitory concentration and strong antimicrobial activity, and it has become the most widely used quinolone in clinical application. Ureaplasma urealyticum is a kind of mycoplasma, which is a common parasitic mycoplasma in the genitourinary tract. Ureaplasma urealyticum infection often need to choose sensitive antibiotics for treatment, the more commonly used drugs are mainly tetracyclines, macrolides and quinolones. Moxifloxacin hydrochloride is a type of quinolone, therefore, it can be used for Mycoplasma Urealyticum infection. If the diagnosis of Mycoplasma Urealyticum infection is confirmed, it is recommended to do drug sensitivity test first, and choose the sensitive antibiotic according to the test result, which can be more effective.