The hand feels swollen and painful to hold the fist not to consider physiological factors and pathologic factors, for the cause of the application of hot compresses, the application of medication. 1. Physiological factors: may be often in the hands of the sagging position caused by poor venous return, blood stasis caused by the occurrence of this situation can be used towel in the local hot compresses, you can also soak your hands in warm water to improve local blood circulation. You can do more fist movements and raise the upper limbs at night to promote blood circulation. 2. Pathological factors: such as rheumatoid arthritis, if both hands will have symptoms of swelling and pain, you can apply non-steroidal painkillers under the guidance of the doctor, such as indomethacin or nimesulide capsules, if there is no improvement, you need to go to the hospital rheumatology and immunology department to check. It is best to go to the hospital for examination to clarify the cause of the disease and then treat it.