Constipation can take drugs include: First, intestinal probiotics, now research found that the supplementation of intestinal probiotics can relieve constipation in some patients, such as the commonly used Methandien, rectification, bifidobacteria, etc. Second, drugs that promote the movement of the gastrointestinal tract can be used, such as morpholine, Mosapride, Cisapride and Sinipride, etc., to promote the movement of the gastrointestinal tract can relieve the symptoms of constipation. Third, for some patients with severe constipation can consider the use of laxatives to help constipation relief, such as osmotic laxatives lactulose, magnesium sulfate, and polyethylene glycol, etc., should start in small doses and gradually increase, lactulose 15-30ml, 2 times a day. It is recommended to try not to take stimulating laxatives, such as rhubarb, aloe vera, castor oil, etc., because long-term use of these drugs may lead to nerve damage in the colonic mucosa and even lead to the possibility of colonic melanosis.