The time required for hypertensive nephropathy to progress to uremia ranges from a few years to decades, and is very much related to the patient’s condition and blood pressure control, so it cannot be generalized. Hypertensive nephropathy is categorized into primary hypertensive kidney injury and malignant hypertensive nephropathy. Malignant hypertensive nephropathy progresses to uremia in a relatively shorter time, while primary hypertensive kidney injury progresses to uremia in a longer time, but the specific time is more related to the individual’s condition and blood pressure control. If it is the early stage of hypertensive nephropathy, only manifested as increased nocturia, decreased urine specific gravity and other renal tubular injury, no creatinine increase, at this time, strict control of blood pressure, the patient’s progression to uremia is relatively long, and even can be lifelong without progression to uremia. If malignant hypertensive nephropathy or primary hypertensive nephropathy with elevated creatinine and poor blood pressure control, the time to enter uremia is relatively short, and may even progress to uremia within a few years. Patients with hypertensive nephropathy need to actively control blood pressure and actively treat complications such as renal anemia to slow down the decline of renal function. It is recommended that patients with hypertensive nephropathy should go to the hospital in time, and under the guidance of the doctor, actively treat the disease to slow down the progress of the disease.