Cholecystitis with hepatic fibrosis can be treated with medication as prescribed by the doctor and surgery if necessary. For cholecystitis with hepatic fibrosis, symptomatic medication should be used as prescribed by the doctor. If the patient is in the acute stage of cholecystitis, he should be fasted and dehydrated, and nutritional support should be given intravenously. Cholecystitis patients can also be prescribed with atropine, pethidine and other antispasmodic analgesic, aminobenzylpenicillin, cefuroxime and other antibiotic treatment. Patients may also be treated with oral choleretic drugs such as 50% magnesium sulfate and ursodeoxycholic acid tablets. If the condition of cholecystitis is serious, cholecystectomy, cholecystostomy and other surgical treatments can be performed as prescribed by the doctor. For the phenomenon of hepatic fibrosis, it can be prescribed with diammonium glycyrrhizinate, magnesium isoglycyrrhizinate and other glycyrrhetinic acid preparations, which can improve the fibrosis. Some patients can also use obeticholic acid to achieve choleretic and hepatoprotective effects, and polyenophosphatidylcholine anti-fibrosis. It is recommended that patients with cholecystitis and hepatic fibrosis should be actively treated under the guidance of a physician, and should not use drugs indiscriminately or adjust the dosage of drugs on their own. Pay attention to the rationality of daily diet, and appropriate exercise when the condition permits.