Should lung cancer be treated in the elderly?

  Lung cancer has become the number one killer that threatens human health, and with the aging of society there are more and more elderly lung cancer patients. Should elderly people with lung cancer be treated? Let’s take a look at the UK report: lung cancer has become the largest cause of death among 39,000 newly diagnosed cancer cases in the UK in 2006, with a 5-year survival rate of 6.5%-7.5%. As the UK ages, the average age at diagnosis of lung cancer patients is rising. The peak incidence is concentrated in the 75 to 79 age group. It is noteworthy that the largest proportion of lung cancer patients are over 75 years of age, almost twice the national average age, so we need to revisit the treatment strategy for lung cancer at advanced ages.  For these reasons, a research group led by Prof. A.M. et al. at London Hospital, UK, reviewed the treatment, radiological and pathological data of newly diagnosed lung cancer patients from January 2002 to December 2004, from which data were collected on statistical surveys of the patient population to study histological types of disease analysis, and treatment outcomes, and this was analyzed. Lung cancer treatment strategies for the elderly were explored by comparing data from patients under 75 years of age and those over 75 years of age. A total of 367 lung cancer cases were analyzed in this study group, with a median age at diagnosis of 72 years and a median survival time of 5.2 months. The older patients had relatively poor data completeness, such as histological confirmation, stage of disease, and PS score, with statistically significant differences. The older the patient, the less chance of receiving active treatment. Patients with lower age had a better physical status and were more likely to receive active treatment. There was no statistically significant difference in the hazard of death ratio of 1.36 between patients above 75 years of age compared to those below 75 years of age. Patients who were treated aggressively, had better physical status and were in the early stages of the disease had a longer median survival time compared to younger people.  This study suggests that although older patients with lung cancer are unlikely to be fully treated aggressively, mainly due to conservative attitudes of patients and clinicians, the survey showed that older patients receiving aggressive treatment had similar survival advantages compared to younger patients. The results of this study shed new light on traditional treatment strategies for older lung cancer patients. Aged lung cancer patients also take should take active measures.