For the copper blue protein, is due to the human body after the intake of copper ions, and plasma globulin binding, and then form copper blue protein, copper blue protein is involved in the body’s copper ion metabolism. If there is a decrease in the amount of copper blue protein, it is considered that the patient may have hepatomegaly, in which case the patient will be poisoned by the accumulation of copper ions in the body. If it is in the liver and other parts of the body, the kidneys and other parts of the body, it will further cause the patient’s hepatic insufficiency, renal insufficiency, as well as the possibility of liver failure and renal failure. If it accumulates in the cranial area and the nervous system, it may affect the development of the nervous system and cause central nervous system symptoms. Such cases should be detected in time. In the patient’s diet, foods with high copper ion content, such as nuts, animal offal, animal fats, and other related foods, should be reduced, and more rest should be paid attention to. If copper metabolism is impaired and copper ions are elevated in the blood, it is important to actively seek medical attention, especially around the cornea to see if there are any specific changes in hepatomegaly.