High blood pressure caused by taking hormones is secondary to hypertension and it is possible to be cured. Hormones are a class of steroidal hormones secreted by the adrenal cortex, including glucocorticoids and hydrocorticoids, and are the main hormones used in response to various stresses. They can also be chemically synthesized. Commonly used hormone drugs in clinical practice include cortisone, hydrocortisone, prednisolone, hydroprednisone, methylprednisolone, and dexamethasone. Exogenous supplemental hormones, whether applied orally or intravenously, cause an increase in aldosterone production in the body. The effect of aldosterone is to cause sodium retention, leading to an increase in blood pressure. If short-term application of hormones blood pressure fluctuations are not significant, longer periods of time will result in higher blood sodium and an increase in blood volume in the body thus causing a rise in blood pressure. For patients who develop high blood pressure after using hormones, measures can be taken such as changing hormone drugs from intravenous to oral and gradually reducing the dosage, and taking antihypertensive drugs. Generally, after stopping the use of hormones, the symptoms of hypertension will gradually improve to cure. Patients who need to apply hormones must use drugs under the guidance of professional doctors, adjust the dose and course of treatment to reduce adverse reactions.