If there is fluid and pus in the lungs and there are holes, it is generally considered to be pneumonia, tuberculosis, lung cancer and so on. Pneumonia and tuberculosis patients are often treated with antibiotics and anti-tuberculosis drugs, while lung cancer patients are recommended to have surgery and other treatments. 1. Pneumonia: Bacterial pneumonia often manifests as a large inflammatory infiltration shadow or solid shadow, with acute onset, often accompanied by high fever, chills, cough, chest pain and other symptoms, and a small amount of fluid accumulation in the angle of rib diaphragm. After anti-infection treatment, pseudo-cavity phenomenon may occur due to the rapid absorption of the lesion. Commonly used drugs include ceftriaxone sodium, penicillin sodium and other antibiotics. The choice of antibiotics can be combined with the patient’s sputum culture and drug sensitivity test. 2. Tuberculosis: when the caseous necrotic material is dissolved and discharged in patients with tuberculosis, the surrounding fibrous tissue is wrapped, forming a cavity, and at the same time, when tuberculosis mycobacteria invade the pleura, there may be pleural effusion, which is commonly used in clinic as anti-tuberculosis treatments, such as isoniazid and rifampicin. 3. Lung cancer: the tumor foci grow rapidly, the cancer tissues are ischemic and necrotic, forming cavity or lung abscess. If accompanied by pleural fluid, it often suggests that the cancer cells have invaded the pleura or the tumor has compressed the lung lymphatic vessels. Lung lobectomy combined with lymph node dissection is recommended for early stage lung cancer, and chemotherapy may be needed for middle and late stage, and the commonly used regimens include gemcitabine combined with carboplatin. There may be other reasons for fluid and pus in the lungs and holes, so it is recommended to consult a doctor in time and standardize the treatment under the guidance of a doctor. The above drugs should be used under the guidance of a physician.