Gallbladder stones do not necessarily require removal of the gallbladder. If there are no symptoms, no treatment is required. If there are surgical indications such as recurrent biliary colic symptoms, large number of stones and large diameter, then the gallbladder needs to be removed. Determining whether gallbladder stones require removal of the gallbladder should be based on the actual condition and cannot be generalized, and there is a certain degree of variability in their treatment. Usually, for patients with no symptoms of gallbladder stones, there is no need to implement the treatment, usually need to carry out abdominal ultrasound examination on time, so that doctors can understand the changes in the condition of the gallbladder, so gallbladder stones do not necessarily need to remove the gallbladder. For patients with recurrent biliary colic, a large number of stones with a diameter of ≥2~3 cm, cholecystitis, obstruction of the common bile duct and other complications, it is necessary to choose timely surgical treatment to remove the gallbladder, and common surgical methods include laparoscopic cholecystectomy, open cholecystectomy and so on. After the operation, patients need to pay attention to rest, and follow the doctor’s instructions to take medication on time, so as to avoid postoperative complications, affecting the therapeutic effect. To summarize, patients with gallbladder stones need to strengthen their daily life management, adjust their dietary structure, and go to the hospital for follow-up on time.