Drinking cola has no effect on the nucleic acid test, the nucleic acid test will not affect the result because of drinking cola, but it is not recommended to drink cola before the nucleic acid test, and you should not eat stimulating food before the nucleic acid test. Drinking cola generally does not affect the results of the nucleic acid test, the nucleic acid test is mainly to detect whether there is a viral infection in the secretion. It is not recommended to drink cola before the nucleic acid test because the nucleic acid test is performed by taking throat swabs or nasal swabs, etc., and cola is irritating, so drinking cola before the test may cause nausea, vomiting and other adverse reactions during sampling. It is recommended that patients avoid eating irritating foods, such as chili peppers and peppercorns, before the nucleic acid test to prevent nausea and vomiting during sampling. Drinking cola usually does not affect the results of nucleic acid test, try to avoid drinking cola before the test to prevent discomfort. It is recommended to avoid talking with others and keep a proper distance to avoid cross infection when doing nucleic acid test.