The reasons for waking up with shoulder and back pain may be overwork, myofasciitis, sports injuries, cervical spondylosis, heart disease and so on. 1. Overexertion: If you are overworked or exercise too much before going to bed, it can lead to the accumulation of local lactic acid, causing physiological pain in the shoulders and back after waking up, which can be relieved after rest. 2. Myofasciitis: aseptic inflammation of the muscles and fascia of the back of the shoulders due to prolonged strain, cold and other factors can lead to pain symptoms after waking up. 3. Sports injury: heavy physical labor or strenuous exercise during the daytime leads to muscle and fascia injury at the back of the shoulders, and then in the morning, the activity can lead to pain when the original injury site is stretched. 4. Cervical spondylosis: degenerative changes in the cervical intervertebral discs can cause pain in the neck, shoulders and back, which is usually alleviated when resting, and the pain in the back of the shoulders can occur in the morning when getting up and moving around. 5. Heart disease: such as angina pectoris, myocardial infarction and other heart diseases, in addition to the typical symptoms of pain in the precordial area, there may also be left shoulder, back pain in the radioactivity, causing pain in the back of the shoulders after waking up. Wake up shoulder and back pain may also have other reasons, such as ankylosing spondylitis, such as after rest is not obvious or aggravated, should be timely to the regular hospital, complete the relevant examination, clear cause of the disease, and comply with the doctor’s instructions for targeted treatment, so as not to delay the condition.