What is the difference between Udenafil and Sildenafil?

The differences between udinafil and sildenafil are the order of research and development, speed of onset of action, duration of action, adverse effects, contraindications and so on.
1. Development sequence: Sildenafil is a first-generation oral phosphodiesterase 5 inhibitor, and udinafil is a new fifth-generation oral anti-phosphodiesterase 5 inhibitor.
2. Speed of onset of action: Although both Udenafil and Sildenafil are both drugs used in the treatment of male erectile dysfunction, and their mechanism of action is also a selective inhibitor of phosphodiesterase (PDE) V; however, Sildenafil has an onset of action in 30-60 minutes after taking the drug, while Udenafil only takes 30-45 minutes to have an onset of action.
3. Efficacy time: Sildenafil has a half-life of about 3-5 hours, while Udenafil has an efficacy of up to 8-12 hours, which is characterized by fast onset of action, mildness, and suitability for diabetic patients.
4. Adverse reactions: Sildenafil may cause facial edema, shock, fatigue, abdominal pain, chest pain, angina, tachycardia, vomiting, diarrhea, abnormal ejaculation, etc.; Udenafil adverse reactions are not clear.
5. Contraindications: sildenafil, prohibited during the administration of nitrate drugs, prohibited for those who are allergic to the ingredients, cardiovascular disease, potentially dangerous, cardiac patients, use with caution; udinafil contraindications are not clear.
When there is erectile dysfunction should promptly go to the regular hospital to consult a clear cause of the disease, under the guidance and advice of a specialist doctor to use drugs, it is not recommended to choose their own medication to avoid adverse reactions.