Lymph nodes in the neck are not necessarily serious and most of them are benign lesions, such as benign lymph node hyperplasia and acute lymphadenitis. For benign lymph node hyperplasia, the condition can be observed without special treatment and frequent touching and stimulation are not recommended. In the case of acute lymphadenopathy, treatment with sensitive antibacterial drugs may be considered. Cephalosporins, penicillins and macrolides, such as amoxicillin, clavulanic acid potassium, penicillin and cephalexin, are commonly used for possibly positive cocci, and gradual intravenous infusion should be given if oral medications are not effective. If the local redness and swelling is obvious, magnesium sulfate can be applied as a wet compress, and patients with severe abscess formation should be given timely incision and drainage. The lymph nodes in the neck may also have malignant lesions, such as lymphoma, and in this case, biopsy by excision or ultrasound biopsy is needed to clarify the diagnosis, and bone marrow aspiration can be performed if necessary. In addition, more serious diseases in the lymph nodes of the neck may also be metastatic cancer, which is mostly seen in lung cancer, thyroid cancer and stomach cancer. For cancer with metastatic lymph nodes, it may be impossible to be removed radically by surgery, and further treatment is needed in the medical oncology department of the hospital, such as chemotherapy, radiotherapy and comprehensive treatment.