Generally antisynthetase antibody syndrome can be relieved by medication, but it is not curable and is prone to recurrence. Anti-synthetase antibody syndrome (ASAS) is a group of special syndromes characterized by myositis, interstitial lung disease, fever, and symmetric arthritis. Generally speaking, anti-synthetase antibody syndrome cannot be cured, but timely drug treatment can effectively relieve the symptoms and control the development of the disease, in addition, the recurrence rate of this disease is high. Patients need to use high-dose glucocorticosteroids, such as prednisone, methylprednisolone, etc., and then the doctor will gradually reduce the dosage according to the change of the disease for maintenance treatment. At the same time, most patients need to use immunosuppressive drugs, such as cyclophosphamide and methotrexate. If combined with lung infections, antibiotics such as ceftriaxone and amoxicillin should be used as prescribed by the doctor. To summarize, patients with antisynthetase antibody syndrome need to go to the hospital in a timely manner, cooperate with the doctor for active treatment, and follow up on time.