Hormones generally refer to glucocorticosteroids, glucocorticosteroids long-term application of side effects, hormone shock treatment dose is greater, the main side effects are as follows: First, elevated blood sugar, hormones can cause abnormal glucose metabolism, and even the occurrence of steroidal diabetes. Second, hypertension, glucocorticoids have the effect of sodium and water retention, which can raise blood pressure, and can cause secondary hypertension in serious cases. Osteoporosis and femoral head necrosis, long-term high-dose application of hormones can easily lead to osteoporosis, and can also form femoral head necrosis. Fourth, poor body resistance, poor resistance to infection and other stresses, hormone shock therapy can inhibit its own adrenocortical function, leading to secondary hyperalgesia. Fifth, peptic ulcer, hormones can cause increased secretion of gastric acid, causing diseases such as gastric and duodenal ulcers.