Down’s syndrome screening requires ultrasound and serologic indicators.
1. Ultrasonography: NT examination can find out the skin thickness of the fetal neck, and can also detect whether there is fluid under the skin of the fetal neck; nasal bone examination can detect whether there is nasal bone in the fetus; examination of the heart area can clarify whether there is malformation in the cardiovascular area.
2. Serum blood indexes include the level of alpha-fetoprotein, whether human chorionic gonadotropin is strongly elevated, the level of free estriol, and whether pregnancy-related plasma protein-A is significantly reduced.
Down’s syndrome is an autosomal malformation disease, which will lead to developmental delay, mental retardation, Down’s face, etc. Down’s screening is non-invasive, although the accuracy rate is not 100%, but it can assess the risk of fetal Down’s syndrome, and it should be paid attention to, and follow the doctor’s instructions for Down’s screening.