Children’s generalized bone pain may be caused by trauma, infection, or bone metastasis of malignant diseases. 1. Trauma: If a child suffers from trauma, such as a collision, it may lead to fractures in many parts of the body, which may cause generalized bone pain and accompanied by activity limitation. 2. Infection: it may be caused by inflammation of bone and joint parts or bone marrow, mostly seen in acute septic osteomyelitis, septic arthritis, etc., which often causes bone pain, fever and fatigue, muscle pain and other symptoms. 3. Bone metastasis of malignant diseases: for example, neuroblastoma, lung cancer and other bone metastasis, which often cause bone pain. There may be other reasons for children’s bone pain, it is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.