Chronic gastric atrophic gastritis C2 with gastric sinus erosion is not very serious, but should be given active treatment as soon as possible. Gastric atrophic gastritis C2 belongs to the less severe classification of atrophic gastritis, and clinical atrophic gastritis is usually categorized into C1, C2, C3, O1, O2, O3, 6 types. Chronic gastric atrophic gastritis C2 with gastric sinus erosion, the condition is not serious, but it should be taken seriously and given treatment as soon as possible. If Helicobacter pylori infection is present, drugs such as amoxicillin, clarithromycin, omeprazole and colloidal bismuth pectin can be given. For patients with low or no acid, pepsin combination and multi-enzyme tablets can be given. Combined application of domperidone, mosapride, etc. to increase gastric motility and promote gastric emptying to relieve bloating and nausea. In addition, gastric mucosal protective agents, such as aluminum thioglycollate and teprenone, should be given to promote gastric mucosal repair. After the above comprehensive treatment, most patients can be cured, not very serious. Chronic gastric atrophic gastritis C2 with gastric sinus erosion, it is recommended to consult a doctor in a timely manner, follow the doctor’s instructions for medication, do not self-medication.