Progesterone can be taken on an empty stomach, but if a woman has some gastrointestinal reactions during pregnancy, such as nausea, vomiting, or some women with poor gastrointestinal function can take it after a meal to reduce gastrointestinal discomfort. Progesterone can generally be used to adjust the menstrual cycle, can also be used for fertility preservation treatment, the time to take as well as the dosage varies from case to case. If a woman has a premonition of miscarriage during pregnancy, and low progesterone is found through examination, oral natural progesterone is given, such as progesterone capsule 100mg twice/day for 7 days, and the progesterone is rechecked again after 7 days to find out the rise of progesterone. Progesterone can also be given to promote menstruation if some women have thickened uterine lining due to irregular menstruation, after pregnancy has been ruled out.