Bumps inside the mid-portion of the penis may be circumcision, folliculitis, eczema, inflammatory polyps, etc., and its treatment is mainly medication, common medications are erythromycin ointment, mupirocin ointment, hydrocortisone cream, tacrolimus ointment and so on. 1. circumcision: usually due to the foreskin urine deposition, after the shedding of the foreskin endothelial cell formation. Generally every day to develop the habit of cleaning can, without special treatment, with time can slowly subside. 2. Folliculitis: the pimples inside the middle of the penis may also be the occurrence of folliculitis, the surface will have pimples, accompanied by swelling and discomfort. It can be treated with erythromycin ointment and mupirocin ointment. 3. Eczema: bumps on the penis can also be caused by eczema, usually accompanied by itching, patients can use hydrocortisone cream, tacrolimus ointment, etc. to relieve the symptoms. 4. Inflammatory polyps: If the bumps inside the mid-portion of the penis are inflammatory polyps, you can use erythromycin ointment for anti-inflammatory treatment. The above drugs should be used under the guidance of a doctor. In addition to the above factors, there are many other possible causes that require different treatments. It is recommended that patients go to regular hospitals for timely consultation and treatment, and strive for early recovery.