The efficacy of Bisoprolol is to slow down the heart rate and reduce myocardial contractility, clinically it is mainly used in the treatment of hypertension, coronary heart disease, heart failure and other diseases, patients should follow the doctor’s instructions to use the drug. Bisoprolol is a β1-adrenoceptor blocker, which can act on the cardiac β-receptor to reduce the body’s response to sympathoadrenergic activity, slowing down the heart rate, reducing myocardial contractility, thereby reducing cardiac output and oxygen consumption. Bisoprolol is used clinically for the treatment of hypertension, coronary artery disease, or for the treatment of moderate to severe chronic stable heart failure with ventricular hypoconstriction after treatment with diuretics, ACE inhibitors (angiotensin-converting enzyme inhibitors) and selective use of cardiac glycosides. Bisoprolol is contraindicated in persons who are hypersensitive to any of the components of the drug, as well as in patients with cardiogenic shock, sinus block, sick sinus syndrome, severe bronchial asthma, metabolic acidosis, second- or third-degree atrioventricular block, acute heart failure or in the decompensated phase of heart failure, symptomatic hypotension or bradycardia, pheochromocytoma. Some patients may experience adverse reactions such as dizziness, headache, bradycardia, hypotension, coldness or numbness of extremities, nausea, vomiting, diarrhea, constipation, rash, fatigue and other adverse reactions after using Bisoprolol, if the discomfort symptoms are more serious should be promptly seek medical attention. Patients should follow the doctor’s instructions to take Bisoprolol, avoid self-medication, so as not to affect the condition, or side effects.