Prolonged menstruation at the age of 50 may be caused by changes in hormone levels, endocrine disorders, endometrial polyps or submucosal fibroids. 1. Changes in hormone levels: At the age of 50, women’s ovarian function gradually decreases, and the level of estrogen and progesterone gradually decreases, which significantly affects menstruation and may cause prolonged menstruation. 2. Endocrine disorders: When women are 50 years old, if they are mentally or psychologically stimulated, they may suffer from endocrine disorders, which may lead to menstrual disorders and prolonged menstrual periods. 3. Endometrial polyps or submucosal fibroids: At the age of 50, if a female patient develops endometrial polyps or submucosal fibroids, her menstrual flow and uneven shedding of the uterine lining may cause prolonged periods. Prolonged periods at the age of 50 are recommended to seek timely medical attention to avoid delaying the condition.