The increase in pulse pressure difference usually has the following factors: 1, the age of the factors, as people grow older, there will be an increase in the degree of atherosclerosis, arterial blood vessels become less elastic, brittle, so there will be an increase in pressure difference, suffering from hypertension, and coronary atherosclerotic heart disease, will make the arterial blood pressure difference increased. 2, if there is long-term hypertension and lead to increased myocardial load, resulting in heart chambers 3. Patients with renal insufficiency, such as chronic renal failure, will also experience an increase in the spread, and must be seen by a hospital in a timely manner if there is an increase in differential pressure.