Palpation of particulate matter with a finger deep in the anus may be due to sinusitis, thrombosed hemorrhoids, anal papillomas, and condyloma acuminatum. Hemorrhoids generally can not be touched, only thrombosed hemorrhoids can be touched . 1. anal sinusitis: generally refers to the sinuses, the anal valve occurs acute and chronic inflammation, manifested as anal pain, defecation, anal itching, perineal discomfort, anal internal particles and other symptoms, follow the doctor’s advice can be oral azithromycin, amoxicillin and other drugs for relief treatment. 2. thrombosed hemorrhoids: generally refers to the anal cushion pathologically downward or anal subcutaneous blood flow stagnation blood vessel rupture of the formation of painful, hard nodules, touching the obvious granularity, that is, thrombosed hemorrhoids. Manifested as blood in the stool, prolapse, swelling and pain, internal anal particles and other symptoms, in accordance with medical advice can be used externally hemorrhoid cream, hemorrhoid suppository and other medications. 3. anal papilloma: generally refers to the anal papilla long-term fecal or chronic inflammation and other stimuli and enlargement, hardening, prolapse outside the anus, manifested as anal itching, swelling and pain, defecation, bleeding, anal papilla prolapse, anal particles and other symptoms, follow the doctor’s instructions can be used to wash potassium permanganate solution, or oral ceftazidime and other drugs for treatment. 4. Warts: Perianal skin is infected by human papilloma virus, causing perianal or intra-anal superfluous organisms, i.e. warts, with an anal foreign body sensation, itching, anal local bleeding and other symptoms, touching the phenomenon of particles in the anus. Finger deep into the anus to feel the particles, need to go to the hospital in time to confirm the diagnosis, under the guidance of the doctor to standardize the treatment, not blindly on their own medication, to avoid causing adverse reactions.