Tacrolimus Ointment has anti-inflammatory and immunomodulatory properties, and side effects such as itching, burning sensation, headache, and susceptibility to infections may occur after use. Tacrolimus ointment is a topical drug, belonging to the immunosuppressant, with anti-inflammatory, antipruritic, anti-allergic and immunomodulatory effects, it can be used for the treatment of atopic dermatitis, seborrheic dermatitis, eczema, etc. It is usually used as a short-term or intermittent long-term treatment, and it is important to pay attention to the fact that it should not be used for a long period of time. Side effects such as itching, burning, and hyperpigmentation may occur locally on the skin after the use of this drug, and systemic side effects such as headache, backache, flu-like symptoms, and susceptibility to infection may also occur. This drug is contraindicated in people who are allergic to this drug and its ingredients, in children under 2 years of age, and should be used with caution by women during pregnancy and lactation. It is recommended to standardize the use of this drug under the guidance of a doctor to avoid affecting the treatment of the disease or serious adverse consequences.