1.Hereditary factors: Here we are not saying that glioma is hereditary, but the possibility of glioma in such people will increase due to the existence of some hereditary factors, especially the existence of certain defects of oncogenes, in the presence of exogenous factors. 2.Ionizing radiation: The chance of glioma will be increased by long-term exposure to the environment with radiation, such as Х-rays, γ-rays, nuclear radiation, etc. 3.Infection: Some animal experiments have confirmed that certain viral infections can induce brain tumor, especially during pregnancy, which is a greater threat to the future of fetus. 4.Good living habits: such as favoring certain kinds of food, drinking alcohol, smoking, etc. Although there is not enough evidence to prove that these factors are related to the occurrence of glioma, it has been confirmed that they are related to the occurrence of gastrointestinal tumors and lung tumors, etc. 5.Tumor origin: There are theories that tumors occur because the embryonic residual foci of primitive cells grow into tumors, and these residual cells can be stimulated by inflammation and cause chronic proliferation to form tumors. Multiple gliomas or gliomatosis may have more than one tumorigenic center.