There are various reasons for creatinine elevation after unilateral nephrectomy. There are transient elevation, which can generally recover by itself and can be continued to be observed without special intervention; there are also pathologic reasons, which are mainly treated with causative and symptomatic treatments including dietary modification, treatment of the primary disease, protection of renal function and continuous renal replacement therapy.
1. Continuous observation: it is common in one-time intake of large amount of protein, strenuous exercise, etc. As the waste is metabolized by the kidneys, creatinine can be gradually restored to the normal range.
2. Dietary regulation: According to the control of blood pressure and generalized edema, salt intake can be reduced, protein intake can be controlled, and low-salt and high-quality protein diet is recommended.
3. Treatment of primary disease: If there are relevant pathological changes in the kidney, such as glomerulonephritis, nephrotic syndrome, IgA nephropathy, etc., we should actively treat the primary disease, and the commonly used drugs are glucocorticoid and cyclophosphamide.
4. Protecting renal function: commonly used drugs to improve microcirculation, such as Danshen drip pill, Bailing capsule, etc. In addition, angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers also have the function of reducing urinary protein.
5. Continuous renal replacement therapy: including hemodialysis and peritoneal dialysis, which can directly remove the body’s metabolic waste and excess water.
Unilateral nephrectomy if the opposite side of the kidney function is good generally have no significant impact on the human body, creatinine is the body’s protein metabolism products, through the excretion of the kidneys out of the body, roughly reflecting the renal function, if creatinine is elevated should go to the hospital in a timely manner, pay attention to the review, to find out the cause of the disease, and under the guidance of the doctor to carry out the relevant treatments.