It is well known that the earlier the disease is detected and treated, the better the treatment will be! Many patients who are detected with gastrointestinal mesenchymal tumors are already very large or have reached advanced metastases. So how can the disease be detected earlier? Generally speaking, gastrointestinal mesenchymal tumors originate from the digestive tract and then grow into the digestive tract or abdominal cavity. There are few symptoms in the early stage, so once abdominal pain, abdominal distension or a lump is felt, the lump is often already relatively large. In some patients, small submucosal occupations are occasionally found due to other diseases of the stomach or during gastroscopic physical examination. However, it is important to note that not all submucosal occurrences are mesenchymal tumors of the gastrointestinal tract; some patients have nerve sheath tumors, ectopic pancreas, lipomas, smooth muscle tumors, etc. Therefore, there is no need to be alarmed by the discovery of submucosal masses in the GI tract. In addition to the usual tests, we usually perform a series of ancillary tests to help clarify the diagnosis in patients with suspected gastrointestinal tract mesenchymal tumors. For example, on plain gastroscopy, gastrointestinal mesenchymal tumors appear as submucosal hemispheres; elevated, smooth mucosal surfaces, and rarely, localized erosions and ulcers. We further perform ultrasound endoscopy, which can clearly divide the gastrointestinal tract into different levels, so that the origin level, size, density, growth direction and depth of infiltration of the mass can be clarified, and sometimes the mass can be found to be fatty, so it can be diagnosed as a lipoma, or if it is found to be very similar to the pancreas, then it should be considered a displaced pancreas. Sometimes a 2 cm occupancy under gastroscopy is found to be actually a 6 cm mass after ultrasound examination. If necessary, the lesion can also be biopsied by ultrasound endoscopy-guided puncture. Therefore, ultrasound endoscopy must be performed before treating gastrointestinal mesenchymal tumors. Secondly, enhanced CT and MRI are also useful for diagnosing and assessing the extent of the tumor. They can clarify the size and density of the mass, the presence of necrosis and bleeding, the accumulation of other important surrounding organs, including the spleen, pancreas, bladder or large important blood vessels, and can also detect the presence of liver and other distant metastases, which can be helpful in determining a good treatment modality for gastrointestinal mesenchymal tumors. In addition, PET-CT can provide a comprehensive assessment of the systemic pathogenesis of the tumor lesion. Therefore, when you or your relatives or friends visit a doctor and are faced with a large number of examination orders, please believe that the doctor is from the same point of view as you, hoping to help you discover the cause of your discomfort through the examination, and try to cooperate with the examination so that the disease can be diagnosed and treated early.