Patient: (mesenteric) gastrointestinal mesenchymal tumor with less than 5 nuclear divisions/50 HPE, volume: 11.5 x 8.5 x 8.0 M. The lesion is highly aggressive risk, immunohistochemistry, CD117 (+), CD34 (-), DOG-1 (+), S-100 (-), CD68 ( -), SMA (+), Kit less than five percent. Three years ago, abdominal pain, suspected appendicitis, was relieved. on the evening of December 5, 2010, abdominal pain worsened and vomiting occurred. On December 6, 2010, he went to the hospital, which misdiagnosed acute appendicitis, incised the abdomen and found intra-abdominal bleeding, intraoperative hemorrhage, approximately 1500 ml, and after exploration, a tumor was found in the mesentery of the small intestine in the left abdomen. The size of the tumor was 11.5×8.5×8.0, bleeding and necrosis, and the tumor was removed and discharged from the hospital on December 25, 2010. About 40 days after surgery, abdominal fluoroscopy was performed and about 3 tumors were found, and abdominal CT showed occupational changes in the small intestine area. Since the discovery of the disease, I have been seeking a more stable treatment method. Questions: 1. What is the next treatment plan? Is it suitable for secondary surgery? 2.What auxiliary tests are available to detect peritoneal metastasis? 3. How long can I survive if I take Grimwell orally? 4. Is there any other good treatment for this disease? Doctor: Gastrointestinal mesenchymal tumor is a malignant tumor of mesenchymal tissue origin with a high incidence. Surgery is the most curable treatment. This patient is a post-operative gastrointestinal mesenchymal tumor with a tumor volume greater than 10 cm in diameter and a ruptured tumor, which is a high risk grade. CD117+. The treatment option should be Imatinib mesylate (Gleevec) oral therapy. Direct surgery should not be performed. Tumor recurrence has been confirmed there is no need to further determine the presence of peritoneal metastases. After one phase of Gleevec treatment (routinely 2-3 months), tumor size reduction or stabilization can be considered for surgical resection.