A blister-like lesion on the genitals is considered to be genital herpes. It is usually a sexually transmitted disease caused by herpes simplex virus type 2 infection, which can be transmitted through sexual contact. The treatment is usually based on oral antiviral drugs, most commonly acyclovir and valacyclovir, and the lesions can be disinfected topically with iodophor to avoid secondary bacterial infection of the lesions. As genital herpes is a highly recurring disease, it is recommended that patients should exercise and take rest to enhance the body’s immunity, which can reduce the chances of herpes recurrence. It may also be due to other diseases such as folliculitis of the skin. So when the above clinical symptoms appear, you should go to the hospital and let the doctor determine what the specific disease is caused by.