Pimples on the face may refer to acne, and the treatment mainly includes topical medication, oral medication, and may also be treated by surgery. 1. Topical medication: Acne is related to Propionibacterium acnes infection, by applying fusidic acid and benzoyl peroxide externally, they have the effect of killing Propionibacterium acnes and anti-inflammatory. Vitamin A acid drugs, commonly used in the clinic, such as vitamin A acid ointment and adapalene gel, can improve the keratinization of sebaceous gland ducts and dissolve acne. 2. Oral drugs: oral doxycycline, minocycline, has the effect of killing Propionibacterium acnes. Isotretinoin and viamin can improve follicular sebaceous gland duct keratinization and dissolve acne. For outbreaks of acne and severe acne, prednisone and dexamethasone can be given in small doses for a short period of time to quickly relieve the inflammatory response. 3. Physical therapy: If acne forms cysts and medication is ineffective, cyst incision and drainage can be used to drain the contents of the cysts and promote the recovery of the cysts. It can also be treated by acne removal, photodynamic, red and blue light irradiation. The appearance of multiple acne, pimples and other skin damage on the face, forehead and back during adolescence is recommended to pay attention to the care of the affected area, but also to the hospital dermatology department, under the guidance of the doctor’s treatment.