Great aunt refers to menstruation. The absence of menstruation for a long time may be caused by pregnancy, menopause, endocrine disorders and other factors. 1. Pregnancy: Women in childbearing age, after pregnancy, will cause menstruation to be absent for a long time, which can be detected through early pregnancy test paper, and if necessary, can be diagnosed through blood HCG, ultrasound and other tests. 2. Menopause: After menopause, older women will lose their menstruation, indicating that they have lost their fertility, which is a normal physiological change and will not cause too much impact. 3. Endocrine disorders: For example, polycystic ovary syndrome, pituitary tumor and other factors may lead to endocrine disorders, which may cause menstruation not to come for a long time, and may be accompanied by excessive menstruation, menstrual bleeding and other abnormal manifestations, and may even affect the fertility of women. For patients who do not have menstruation for a long time, it is recommended to seek medical treatment to avoid adverse effects.