Rheumatoid can not just take hydroxychloroquine, hydroxychloroquine is an immunomodulator, often used as a combination therapy drug. Rheumatoid first-line therapeutic drugs for the traditional improvement of the condition of anti-rheumatic drugs, preferred methotrexate. For rheumatoid patients with relatively mild conditions, simply taking hydroxychloroquine has a certain effect, because hydroxychloroquine has an anti-inflammatory, immunomodulating effect, can assist in improving the symptoms of rheumatic diseases, can reduce the condition, delay joint destruction. Clinical treatment of rheumatoid hydroxychloroquine is often used as a combination of therapeutic drugs, rarely used alone. Rheumatoid treatment is preferred to traditional synthetic anti-rheumatic drugs, such as methotrexate, leflunomide and so on. In the acute phase, anti-inflammatory and analgesic drugs, such as diclofenac sodium tablets and prednisone tablets, may also be used in combination. If the condition is severe, treatment should also be combined with biologics, such as etanercept and infliximab. Adverse effects of hydroxychloroquine are retinal pigmentation and visual field defects, skin rashes, gastrointestinal disorders, sensory-motor nerve diseases, etc. Hydroxychloroquine tablets should be contraindicated in people who are allergic to the ingredients of hydroxychloroquine tablets, the presence of fundus macularis, and in children under 6 years of age. Patients taking this drug should have their fundus and visual fields checked at least once a year. Rheumatoid patients need to go to the regular hospital in time, the use of drugs must be taken under the guidance of a professional physician, to avoid unauthorized use of drugs.