Total bilirubin 26.26umol/L and indirect bilirubin 20.1umol/L may be caused by Hepatitis B, or may be caused by cholecystitis, gallstones, liver and gallbladder cancer. In order to check whether you have hepatitis B, you need to do hepatitis B 5 tests, and if necessary, further improve the hepatitis B virus DNA quantification, liver function, liver ultrasound and other tests, you can not rely on the bilirubin alone to determine whether you have hepatitis B or not. Hepatitis B usually manifests itself in the form of right upper abdominal pain, aversion to oil and grease, fatigue, dark color, jaundice and other symptoms. Obstruction of the biliary system may cause elevated total and indirect bilirubin, such as choledocholithiasis, cholangiocarcinoma, hepatocellular carcinoma, etc. Each disease has its own corresponding symptoms, such as jaundice, biliary colic, and fever. People with total bilirubin of 26.26umol/L and indirect bilirubin of 20.1umol/L need to go to the hospital in time to get further clarification of the cause of elevated bilirubin under the guidance of the doctor, and then treat the cause of the elevated bilirubin if necessary.