Both pimples and zits are medically classified as acne, a chronic inflammatory skin disease of the sebaceous gland units of hair follicles. Acne around the mouth can be eliminated through general treatment, medication, and physical therapy. 1. General treatment: Choose water or suitable cleansing products to remove excess oil, flakes and bacterial mixtures from the skin surface, but do not over-wash, pay attention to oil control and moisturizing, and use mild moisturizing milk externally. Avoid squeezing and scratching the lesions with hands. Limit the intake of high glycemic index foods and milk that may trigger or aggravate acne, keep bowel movement smooth, and avoid staying up all night. 2. Medication: mild acne can be treated with medications such as retinoic acid gel and adapalene gel; antibiotics such as fusidic acid cream and erythromycin ointment can also be used for antibiotic and antimicrobial treatments; moderate and severe acne can be treated with oral erythromycin, metronidazole, isotretinoin and other medications; acne accompanied by high androgen manifestations can be orally administered with birth control pills, spironolactone and other medications. 3. Physical therapy: Photodynamic therapy can use the photothermal effect to destroy Propionibacterium acnes and reduce the inflammatory response. If you have acne around your mouth, you should seek medical advice and choose the best treatment under the guidance of your doctor, and avoid using medication privately to avoid delaying your condition.