The skull has its own responsibilities, and only when the skull is intact can the intracranial environment be stabilized and the brain tissues can work properly. Whether the skull defect is caused by traumatic brain injury or craniosynostosis, it is necessary to go to a regular hospital for skull repair surgery to reduce the damage as much as possible. Many people may not know much about cranial repair surgery, especially they are hesitant to make a decision because they are afraid of the high risk of surgery. But in fact, in neurosurgery, cranial bone repair surgery is very classical and has been attempted in this area for a long time. Together with the continuous progress and development of medicine, this surgery has become very mature and safer, and there have been significant advances in repair materials, from early bone cement and plexiglass to the current titanium mesh and polyether ether ketone PEEK materials, which are strong evidence. After extensive clinical practice and comparison, polyetheretherketone PEEK materials are now superior and the restorative results are particularly desirable. What is polyetheretherketone material? Polyetheretherketone PEEK is a new type of polymer material with excellent overall performance, such as high temperature resistance, corrosion resistance, fatigue resistance, wear resistance, high strength, high elasticity, and good histocompatibility, comparable to human cranial bone, and is an excellent choice for cranial bone repair. At present, our team has widely used PEEK material to perform surgery, and this new material can be embedded in the repair, not only smooth the postoperative appearance, but also can be shaped in three dimensions according to the patient’s cranial CT data, which can really restore the original physiological structure of the skull to a high degree.