As the protective shield of the brain, the skull assumes an important role for brain tissue. Due to cranial defects caused by external factors such as cranial trauma and disease, brain tissue is vulnerable to secondary injury when it loses cranial protection. In order to avoid this situation, patients need to undergo cranial repair as early as possible so that the intracranial pressure can be restored to a normal and stable state as much as possible and reduce the drastic daily changes in brain pressure caused by the cranial defect. Polyetheretherketone for cranial repair is less used in China at present. Our neurosurgery department has been using polyetheretherketone as cranial repair material for many years with good clinical feedback. Compared with titanium mesh repair material, it is prone to rejection, infection, and poor insulation. Polyetheretherketone, on the other hand, is non-magnetic, has no imaging artifacts, good CT imaging compatibility, light material, thermal insulation after implantation of large blocks, avoiding discomfort caused by temperature difference, perfect anatomical reconstruction shape, good histocompatibility, mechanical properties close to human bone, and significantly reduced surgical risk. Various properties of polyetheretherketone material are obviously better than traditional titanium mesh, so how much does it cost to choose polyetheretheretherketone for cranial repair? In fact, the cost of polyetheretherketone for cranial repair is based on the patient’s condition, the size of the polyetheretherketone material used and other factors to determine the patient’s cost. This surgery can not be done in all surgical hospitals, and the requirements for the surgeon’s experience, surgical skills and anesthesia dose are very strict.