Causes of vulvar pain include infectious and non-infectious factors, and need to be treated with different medications for different causes. It is necessary to use drugs correctly under the guidance of the doctor. Infectious factors include bacterial infection, viral infection, fungal infection, mycoplasma infection and so on; non-infectious factors include endocrine disorders, physical friction, trauma and so on. 1. Vulvar pain caused by bacterial infection can take antibiotics such as roxithromycin, azithromycin, clindamycin and other drugs to control inflammation. 2. Viral infections can take antiviral drugs such as acyclovir and vasiclovir to treat the disease and control the infection. 3. Fungal infections, such as Candida infection caused by vulvovaginosis can be treated with drugs such as clotrimazole suppositories or miconazole nitrate vaginal soft capsules. 4. Vulvovaginitis caused by mycoplasma infection can be treated with erythromycin ointment, azithromycin and other drugs. 5. Endocrine disorders such as decreased levels of estrogen may cause pain in the vulva and can be treated with medications such as estradiol and nil estradiol to improve symptoms. 6. Vulvar pain caused by physical friction, burns, etc. can be treated by applying lidocaine gel or taking drugs such as diclofenac sodium extended-release tablets. There are many other causes of vulvar pain, you need to choose the most suitable drugs under the guidance of a doctor, you need to follow the doctor’s instructions for the correct use of medication, adverse reactions recommended to consult a doctor, allergic to the drug is prohibited to use the drug.